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The list price of Merck & Co.'s diabetes pill Januvia is cut in half on average by estimated discounts, according to the SSR Health data. Even so, Merck gets more than twice as much in the U.S. for a monthly supply of the same drug as in Canada, the next most costly place to buy it, Bloomberg found. Humira, AbbVie Inc.'s best-selling rheumatoid arthritis treatment, costs an estimated $2,500 a month in the U.S. after discounts, compared with about $1,750 in Germany, Bloomberg found. In other nations, the drug's price drops even lower.
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To counteract the impact of the patent cliff, AstraZeneca has made strong forays into immuno-oncology, cardiovascular, and metabolic diseases. The problem, though, is that developing drugs is expensive, and without blockbusters to replace the huge amounts of revenue that Seroquel, Nexium, and Crestor bring in, AstraZeneca's cash flow will take a big hit. Indeed, the drugmaker has already kept its dividend unchanged for years after a long history of consistent payout increases. In time, any failure to get high-revenue drugs through its pipeline could easily necessitate a dividend cut from AstraZeneca.
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